Tesamorelin

Tesamorelin Peptide Description:

Tesamorelin is a growth hormone-releasing hormone (GHRH) analog that has been shown to increase growth hormone and IGF-1 levels. According to one clinical study, 10.9 percent of patients who were given Tesamorelin experienced reductions in deep belly fat. The study lasted six months in total. Overall, visceral fat levels decreased by eighteen percent. Tesamorelin is a synthetic polypeptide analog of growth hormone-releasing hormone. This growth hormone-releasing factor (GHRF) is similar to the hormone released from the hypothalamus gland in the brain. By mimicking the natural growth hormone-releasing factor, it not only slashes through visceral fat but also potentially enhances lipid profiles, tipping the scales towards healthier cholesterol levels.

Beyond its metabolic advantages, Tesamorelin shines a light on cognitive health, offering a glimmer of hope for improved mental function in older adults or those facing cognitive decline. The peptide’s ability extends to boosting growth hormone levels, laying the groundwork for improved metabolism, physical performance, and a sense of well-being. Furthermore, its role in possibly improving insulin sensitivity marks it as a key player in the management of blood sugar levels, making it a multifaceted ally in the quest for holistic health improvement.

Please note that the statements made regarding this product have not been evaluated by the Food and Drug Administration (FDA). This product is not intended to diagnose, treat, cure, or prevent any disease.

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How does Tesamorelin Work?

Tesamorelin activates GHRH receptors in the pituitary gland. This leads to the synthesis and release of growth hormone, which, in turn, acts on multiple cells of the body to stimulate the production of insulin-like growth factor 1 (IGF-1). IGF-1 mediates many of the effects of the growth hormone, which in the liver include growth, inhibition of programmed cell death, glucose update, and lipolysis. Serum IGF-1 levels tend to be low in patients with obesity, diabetes, and lipodystrophy. [R] Optimize Life sells Tesamorelin for laboratory and research use only.

Tesamorelin Research

Available medical research suggests that Tesamorelin is effective in reducing excess fat in the stomach area in people with HIV-associated lipodystrophy. Furthermore, in a 2012 study, Tesamorelin peptide had positive effects on cognition in research subjects. [R]A clinical trial is ongoing to assess the efficacy of Tesamorelin as a therapy for peripheral nerve injury. The investigators hypothesize that Tesamorelin treatment will allow for faster and greater recovery of motor and sensory function after surgical repair of peripheral nerves. [R]

1) Tesamorelin and Lipodystrophy

Lipodystrophy is a condition that causes a person to lose fat from some parts of the body, while gaining it in others. It occurs in HIV patients who are being treated with antiretroviral therapy (ART). It targets the face, arms, legs, buttocks, and truncal areas. [R] A literature review was conducted to evaluate the efficacy and safety of Tesamorelin for the treatment of lipodystrophy associated with HIV infection.

All articles published in English identified from data sources were evaluated, and all pertinent information was included. The review found that Tesamorelin is effective in improving visceral adiposity and body image in patients with HIV-associated lipodystrophy over 26-52 weeks of treatment. Tesamorelin thus provides a useful treatment option for the management of HIV-associated lipodystrophy. [R]

2) Tesamorelin and Cardiovascular Disease

Clinical research suggests that heart failure and abnormal heart rhythms may be more likely in people living with HIV. Moreover, an analysis of a large healthcare database showed that HIV-infected individuals are at an increased risk of developing cardiovascular disease. [R] [R] In a randomized trial involving HIV patients, the levels of triglycerides decreased by 50mg per deciliter in the Tesamorelin group, compared with 9 mg per deciliter in the placebo group. Levels of total and HDL cholesterol also improved significantly in the Tesamorelin group. [R]

3) Tesamorelin and Body Composition

Tesamorelin selectively reduced visceral adipose tissue (VAT) in a randomized, double-blind, placebo-controlled study. Other body composition parameters, including waist circumference, total fat, and lean body mass, improved in the Tesamorelin vs. placebo groups. There were no serious adverse events during the study. No significant difference in the rats of adverse events between Tesamorelin and placebo groups was observed. [R]

4) Tesamorelin and Cognition

According to a study published in Archives of Neurology, administering Tesamorelin to patients with mild cognitive impairment or healthy older adults has positive effects on cognition. The researchers recruited 152 adults for the study, of whom 137 completed it. Tesamorelin improved executive function and, to a lesser degree, short-term verbal memory. Cognitive function improved in healthy adults, and the expected functional decline of those with mild cognitive impairment was attenuated. [R] Optimize Life sells Tesamorelin for testing and laboratory experimentation and not for human consumption.

5) Tesamorelin and Memory

A randomized, double-blind, placebo-controlled trial demonstrated that Tesamorelin administration has a favorable effect on verbal memory for adults with mild cognitive impairment (MCI), who are at a high risk of progression to Alzheimer’s dementia. [R]

*Please note that the statements made regarding this product have not been evaluated by the Food and Drug Administration (FDA). This product is not intended to diagnose, treat, cure, or prevent any disease.

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This product is sold as a pure compound for research purposes only and is not meant for use as a dietary supplement. Please refer to our terms and conditions prior to purchase.

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